Sleep-Wake Disorders Pharmacology

Sleep-Wake Disorders Pharmacology is the study and application of drugs that treat sleep problems (like insomnia, narcolepsy, circadian rhythm disorders) or excessive sleepiness by targeting brain systems that regulate sleep and wakefulness, using medications to promote sleep (hypnotics like benzodiazepines) or promote alertness (stimulants like modafinil, caffeine, amphetamines), aiming to improve daytime function and quality of life, notes this review article on clinical pharmacology and this MDPI article.
  • ⏱ Duration: 30 Minutes
  • 📘 Lectures: 1
  • 🌎 Language: English
  • 🏷 Skill Level: Intermediate
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Pharmacology for sleep-wake disorders targets systems regulating sleep (like GABA) with drugs such as benzodiazepines (Zolpidem, Lorazepam) and melatonin agonists (Ramelteon) for insomnia, while using stimulants (Modafinil, Amphetamines) or wake-promoting agents (Orexin antagonists) for hypersomnia, and even sedating antidepressants (Trazodone) or antipsychotics (Quetiapine) for specific symptoms, all aiming to balance neurotransmitters like GABA, Histamine, Norepinephrine, and Orexin to improve sleep quality or daytime alertness, though many medications carry risks like dependence or side effects.

0 Quizzes • 1 Flashcard
  • 🧠 Sleep-Wake Disorders Pharmacology Flashcard

Instructor info coming soon.

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